Search results for "supramolecular hydrogel"

showing 3 items of 3 documents

Naphthalimide imidazolium-based supramolecular hydrogels as bioimaging and theranostic soft materials

2020

1,8-Naphthalimide-based imidazolium salts differing for the alkyl chain length and the nature of the anion were synthesized and characterized to obtain fluorescent probes for bioimaging applications. First, their self-assembly behavior and gelling ability were investigated in water and water/dimethyl sulfoxide binary mixtures. Only salts having longer alkyl chains were able to give supramolecular hydrogels, whose properties were investigated by using a combined approach of fluorescence, resonance light scattering, and rheology measurements. Morphological information was obtained by scanning electron microscopy. In addition, conductive properties of organic salts in solution and gel state we…

Materials scienceCell SurvivalMacromolecular SubstancesSurface PropertiesScanning electron microscopeimidazolium salts010402 general chemistry01 natural sciencesTheranostic Nanomedicinechemistry.chemical_compoundbioimaging; fluorescence; imidazolium salts; naphthalimide; supramolecular hydrogelsCell Line TumorPhase (matter)HumansGeneral Materials ScienceParticle SizeSettore BIO/06 - Anatomia Comparata E CitologiabioimagingAlkylFluorescent Dyeschemistry.chemical_classificationMolecular Structure010405 organic chemistryDimethyl sulfoxideOptical ImagingImidazolesHydrogelsBiological activitySettore CHIM/06 - Chimica OrganicaResonance (chemistry)Combinatorial chemistryFluorescencenaphthalimide0104 chemical sciencesNaphthalimideschemistrySelf-healing hydrogelssupramolecular hydrogelsfluorescence
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Biocompatible Hydrogelators Based on Bile Acid Ethyl Amides

2016

Four novel bile acid ethyl amides were synthetized using a well-known method. All the four compounds were characterized by IR, SEM, and X-ray crystal analyses. In addition, the cytotoxicity of the compounds was tested. Two of the prepared compounds formed organogels. Lithocholic acid derivative 1 formed hydrogels as 1% and 2% (w/v) in four different aqueous solutions. This is very intriguing regarding possible uses in biomedicine. peerReviewed

Models MolecularLithocholic acidBiocompatibilitymedicine.drug_classClinical Biochemistrysupramolecular hydrogelMolecular ConformationBiocompatible Materials02 engineering and technology010402 general chemistry01 natural sciencesBiochemistryMicechemistry.chemical_compoundEndocrinologybiocompatibilityAmidemedicineAnimalsOrganic chemistrybile acidMolecular Biologyta116PharmacologyAqueous solutionBile acidOrganic Chemistryta1182WaterHydrogels3T3 Cellsself-assembly021001 nanoscience & nanotechnologyAmidesamide0104 chemical scienceschemistryBiochemistrySelf-healing hydrogelsLithocholic AcidSelf-assembly0210 nano-technologyDerivative (chemistry)
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Inverse Thermogelation of Aqueous Triblock Copolymer Solutions into Macroporous Shear-Thinning 3D Printable Inks

2020

Amphiphilic block copolymers that undergo (reversible) physical gelation in aqueous media are of great interest in ditIerent areas including drug delivery, tissue engineering, regenerative medicine, and biofabrication. We investigated a small library of ABA-type triblock copolymers comprising poly(2-methyl-2-oxazoline) as the hydrophilic shell A and different aromatic poly(2-oxazoline)s and poly(2-oxazine)s cores B in an aqueous solution at different concentrations and temperatures. Interestingly, aqueous solutions of poly(2-methyl-2-oxazoline)-block-poly(2-phenyl-2-oxazine)-block-poly(2-methyl-2-oxazoline) (PMeOx-b-PPheOzi-b-PMeOx) undergo inverse thermogelation below a critical temperatur…

UCSTMaterials science116 Chemical sciencesbiomaterial ink02 engineering and technology010402 general chemistry01 natural sciencesUpper critical solution temperatureCHEMISTRYAmphiphileCopolymerGeneral Materials SciencePOLYOXAZOLINESTEMPERATUREchemistry.chemical_classificationdispense plottingAqueous solutionSUPRAMOLECULAR HYDROGELPolymer021001 nanoscience & nanotechnologyMicrostructure3. Good health0104 chemical sciencesPOLY(2-OXAZOLINE)Spoly(2-oxazoline)POLYMERIZATIONPolymerizationchemistryChemical engineeringwormlike micelles2-OXAZOLINESsmart hydrogelPOLYMERS0210 nano-technologyBEHAVIORBiofabrication
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